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Check with your doctor immediately if any of the following side effects occur:

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of theophylline in the elderlyHoweverelderly patients may be more sensitive to the effects of theophylline than younger adultsand are more likely to have kidneyliverheartor lung problemswhich may require caution and an adjustment in the dose for patients receiving theophylline.

Some side effects may occur that usually do not need medical attentionThese side effects may go away during treatment as your body adjusts to the medicineAlsoyour health care professional may be able to tell you about ways to prevent or reduce some of these side effectsCheck with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Theophylline has two distinct actions in the airways of patients with reversible obstructionsmooth muscle relaxationi.ebronchodilationand suppression of the response of the airways to stimulii.enon-bronchodilator prophylactic effectsWhile the mechanisms of action of theophylline are not known with certaintystudies in animals suggest that bronchodilatation is mediated by the inhibition of two isozymes of phosphodiesterasePDE III andto a lesser extentPDE IVwhile non-bronchodilator prophylactic actions are probably mediated through one or more different molecular mechanismsthat do not involve inhibition of PDE III or antagonism of adenosine receptorsSome of the adverse effects associated with theophylline appear to be mediated by inhibition of PDE IIIe.ghypotensiontachycardiaheadacheand emesisand adenosine receptor antagonisme.galterations in cerebral blood flow

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