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Other drugs may interact with lamivudineincluding prescription and over-the-counter medicinesvitaminsand herbal productsSome drugs should not be used together with lamivudineTell your doctor about all your current medicines and any medicine you start or stop using.

Lactic acidosis and severe hepatomegaly with steatosisincluding fatal caseshave been reported with the use of nucleoside analogues and other antiretroviralsA majority of these cases have been in womenObesity and prolonged nucleoside exposure may be risk factorsMost of these reports have described patients receiving nucleoside analogues for treatment of HIV infectionbut there have been reports of lactic acidosis in patients receiving lamivudine for hepatitis BCaution should be exercised when administering Epivir-HBV to any patient with known risk factors for liver diseasehowevercases also have been reported in patients with no known risk factorsTreatment with Epivir-HBV should be suspended in any patient who develops clinical or laboratory findings suggestive of lactic acidosis or pronounced hepatotoxicitywhich may include hepatomegaly and steatosis even in the absence of marked transaminase elevations

There is no information available regarding the effects of the drug on the breastfed infant or on milk production.

Signs of a new infectionfevernight sweatsswollen glandsmouth soresdiarrheastomach painweight loss;

Patients with peripheral neuropathy can experience exacerbations during lamivudine therapy.

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use epivir-hbv lamivudine as directed by your doctor.


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